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Faculty Image John McCutcheon
Office: Health Sciences 304A
Phone: (406) 243-6071
Email: john.mccutcheon@umontana.edu
Website: Click Here

 

Education:

B.S., Biochemistry, University of Wisconsin—Madison, 1996

M.S., Human Genetics, University of Utah, 2000

Ph.D., Computational Biology, Washington University in St. Louis, 2006

Postdoctoral Fellow, University of Arizona, 2006-2010

Other Publications:

Bennett GM, McCutcheon JP, McDonald BR, Romanovicz D, Moran NA. 2014. Differential genome evolution between companion symbionts in an insect-bacteria symbiosis. mBio, in press. 

Van Leuven JT, Meister RC, Simon C, McCutcheon JP. 2014. Sympatric speciation in a bacterial endosymbiont results in two genomes with the functionality of one. Cell, in press. 

McCutcheon JP and Keeling, PJ. 2014. Endosymbiosis: protein targeting further erodes the organelle/symbiont distinction. Current Biology 24: R654–R655.

Duncan RP, Husnik F, Van Leuven JT, Gilbert D, Davalos, L, McCutcheon JP, Wilson ACC. 2013. Dynamic recruitment of amino acid transporters to the insect-symbiont interface. Molecular Ecology 23: 1608–1623.

McCutcheon JP. 2013. Genome evolution: a bacterium with a Napoleon complex. Current Biology 23: R657–R659.

Brown AMV, Nelson K, Bolender C, McCutcheon JP. 2013. Population genomics of a symbiont in the early stages of a pest invasion. Molecular Ecology 23: 1516–1530.

Husnik F, Nikoh N, Koga R, Ross L, Duncan RP, Fujie M, Tanaka M, Satoh N, Bachtrog D, Wilson ACC, von Dohlen CD, Fukatsu T, McCutcheon JP. 2013. Horizontal gene transfer from diverse bacteria to an insect genome enables a tripartite nested mealybug symbiosis. Cell 153: 1567–1578. 

Van Leuven JT and McCutcheon JP. 2012. An AT mutational bias in the tiny GC-rich endosymbiont genome of HodgkiniaGenome Biology and Evolution 4: 24-27.

McCutcheon JP and Moran NA. 2012. Extreme genome reduction in symbiotic bacteria. Nature Reviews Microbiology 10: 13-26.

McCutcheon JP and von Dohlen CD. 2011. An interdependent metabolic patchwork in the nested three-way symbiosis of mealybugs. Current Biology 21: 1366-1372.

McCutcheon JP and Moran NA. 2010. Functional convergence in reduced genomes of bacterial symbionts spanning 200 million years of evolution. Genome Biology and Evolution 2: 708-718.

Woyke T, Tighe D, Mavromatis K, Clum A, Copeland A, Schackwitz W, Lapidus A, Wu D, McCutcheon JP, McDonald BR, Moran NA, Bristow J, Cheng J. 2010. One bacterial cell, one complete genome. PLoS One 5(4): e10314.

Nikoh N, McCutcheon JP, Kudo T, Miyagishima S, Moran NA, Nakabachi A. 2010Bacterial genes in the aphid genome: absence of functional gene transfer from Buchnera to its host. PLoS Genetics 6(2): e1000827.

The International Aphid Genomics Consortium. 2010. Genome sequence of the pea aphid Acyrthosiphon pisumPLoS Biology 8(2): e1000313.

McCutcheon JP. 2010. The bacterial essence of tiny symbiont genomes. Current Opinion in Microbiology 13: 73-78.

McCutcheon JP, McDonald BR, and Moran NA. 2009. Convergent evolution of metabolic roles in bacterial co-symbionts of insects. Proceedings of the National Academy of Sciences USA 106: 15394-15399.

McCutcheon JP, McDonald BR, and Moran NA. 2009. Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont. PLoS Genetics 5(7): e1000565.

Moran NA, McCutcheon JP, and Nakabachi A. 2008. Genomics and evolution of heritable bacterial symbionts. Annual Review of Genetics 42: 165-190.

McCutcheon JP and Moran NA. 2007. Parallel genomic evolution and metabolic interdependence in an ancient symbiosis. Proceedings of the National Academy of Sciences USA 104: 19392-19397.