The University of Montana
Department of Mathematical Sciences

Technical report #5/2006

A Two Stage Model for Quantitative PCR

Emily Stone and John Goldes
Department of Mathematical Sciences
The University of Montana
Missoula, MT 59801

and

Martha Garlick
Department of Mathematics and Statistics
Utah State University
Logan, UT 84322-3900

Abstract

In this paper we develop a suite of deterministic models for the reactions of quantitative PCR based on the law of mass action. The models are created by adding more reaction species to a base model (the logistic equation). Qualitative analysis is preformed at each stage and parameters are estimated by fitting each model to data from Roche LightCycler (TM) runs..

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